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Scaling Startups In The NHS: Longer term strategies for founders and VCs in the ecosystem.



Healthcare technology and the NHS seem perpetually caught in a paradox. The NHS, birthed from post-war idealism and built on principles of universal care, now finds itself grappling with the sprint-paced world of healthtech innovation. It's a bit like trying to retrofit a Victorian mansion with smart home technology - the potential is immense, but the implementation isn't quite as straightforward as one might hope.


The numbers paint an intriguing picture. Despite the UK healthtech sector's valuation surpassing £24 billion in 2021, and London positioning itself as Europe's leading healthtech hub, scaling within the NHS remains a challenge that has humbled many ambitious founders.


The system's complexity - a labyrinth of trusts, procurement processes, and clinical validations - often feels designed to test the patience of even the most determined entrepreneurs.


Yet, this complexity exists for good reason. When your customer base is effectively the entire UK population, and your products could literally mean the difference between life and death, perhaps a degree of careful consideration isn't just bureaucracy - it's necessity.


For healthtech startups, understanding how to navigate this landscape isn't just about growth - it's about survival. From securing those crucial first NHS contracts to building relationships with individual trusts, and eventually positioning for exit, each stage presents its own unique challenges. In this piece, we'll explore how healthtech startups can scale within the NHS ecosystem, examining both the obstacles and opportunities that lie ahead.



The NHS Innovation Landscape: More Than Just Numbers




The NHS stands as one of the world's largest healthcare systems and has made remarkable strides in embracing innovation. With a £250 million AI fund, the successful Innovation Accelerator programme, and numerous initiatives supporting new technologies, it's creating genuine opportunities for startups to transform healthcare delivery.


The scale of this progress is noteworthy. Through the NHS Innovation Accelerator alone, innovative technologies have been deployed across more than 2,100 sites, delivering £38 million in savings. This expansion continues through the 230 acute hospital trusts and 600 primary care organisations, with each successful implementation helping build a more efficient healthcare system.


Consider Kheiron Medical Technologies, which exemplifies both the transformative potential and measured approach of NHS innovation adoption. Their AI software could save 2,000 lives yearly by catching breast cancers that humans might miss. Since receiving regulatory approval in 2018, they've undertaken comprehensive validation - two large trials, a clinical study, and 16 service evaluations at individual NHS sites. While this thorough process involves significant investment, it ensures patient safety remains paramount.


The NHS's structure reflects its commitment to local needs while maintaining national standards. Rather than operating as a single entity, it functions as a network of interconnected organisations, each serving their community's specific healthcare requirements. This arrangement, while complex, enables trusts to choose solutions that best fit their population's needs. 


The funding model similarly balances efficiency with effectiveness. Clinical Commissioning Groups receive allocated funds, Acute Trusts are paid based on activity, and community and mental health services operate on block contracts. GPs receive funding per registered patient plus targeted incentives - a system designed to ensure resources reach where they're most needed.


Success stories continue to emerge. Through careful collaboration with individual trusts, companies like Patients Know Best have successfully scaled their innovations across the system. Babylon has secured significant NHS contracts, demonstrating the opportunities available for startups bringing valuable solutions to healthcare challenges.


The key learning from these successes is clear: effective innovation in the NHS comes through partnership. Startups that understand the unique needs of individual trusts, while appreciating the broader mission of public healthcare, are finding paths to scale their solutions effectively.




Scaling Within the System: A Practical Guide


The path to scaling within the NHS isn't about quick wins or flashy pitches. It's about understanding how individual trusts operate, what keeps their finance directors up at night, and most importantly - how your solution fits into their broader mission.


Anyone who's tried to sell into the NHS knows that calling it a single buyer is like calling London a village. Each trust operates with its own budget, priorities, and procurement processes. What works in Leeds might not fly in Southampton. This isn't a bug in the system - it's a feature that ensures local needs are met.


Take Lantum, a workforce management platform that grew by solving a real problem: the NHS's £3.5 billion annual spend on doctor recruitment agencies. Rather than trying to boil the ocean, they started with GP Federations, gradually expanding to 40 of them across the UK. Their approach? Understanding that each federation had slightly different needs, then adapting their platform accordingly.


The money side of things requires equal attention. Clinical Commissioning Groups control the purse strings, but they're not just looking for the cheapest option. They need solutions that demonstrate clear value - whether that's cost savings, improved patient outcomes, or ideally both. Tortus, which recently landed its first commercial contract with Great Ormond Street Hospital, spent most of 2022-2023 running clinical trials to prove their AI note-taking tool could give doctors 25% more patient time.


Here's what successful startups typically get right:


Start small and prove it works: 


The NHS Innovation Accelerator isn't looking for unicorns - they want solutions that solve real problems. Skin Analytics began with a focused approach to skin cancer detection and is now live in 16 NHS trusts.


Build relationships at the trust level:


Despite all the talk of national initiatives, most successful implementations start with strong relationships with individual trusts. It's not about sending endless emails - it's about understanding each trust's specific challenges and configuring your solution to address them.


Get the evidence right:

 

The NHS needs more than promises - it needs proof. Clinical validations, cost-benefit analyses, and real-world data are your tickets to the game. This isn't red tape - it's about ensuring patient safety and system efficiency.


Remember you're playing the long game:

 

The NHS procurement cycle moves at its own pace. While this might frustrate VCs looking for quick returns, it actually helps separate serious health tech innovators from those just riding the latest trend.


According to the NHS Providers capital report, 97% of trust leaders report digital and IT investment as their top priority. This isn't just about modernising - it's about solving real operational challenges. The successful startups understand this perfectly.


Brainomix offers a masterclass in this approach. Their AI stroke diagnosis tool is now running in 90 UK NHS stroke centres. The results? Treatment rates are 55% higher than the national average. They didn't achieve this by promising AI would solve everything - they focused on a specific, measurable outcome that mattered to clinicians.


The procurement route matters too. The Beauhurst analysis shows that going through established channels like the NHS Innovation Accelerator can significantly smooth the path to adoption. Since 2015, this programme has helped deploy technologies across thousands of NHS sites - but more importantly, it's helped startups understand how to navigate the system effectively.


Capital constraints are very real - ask any trust finance director. Yet according to Sifted's recent analysis, the UK government has pledged £250m specifically for AI development in the NHS. The money exists, but accessing it requires understanding where your solution fits in the broader transformation agenda.


The secret? Don't treat NHS procurement as a sales process. Treat it as a partnership opportunity. When DrDoctor started working with the NHS, they didn't just sell appointment management software - they worked with trusts to redesign how patient communication worked from the ground up. Now they're helping multiple trusts tackle their waiting list challenges.


For startup founders, the message is clear: yes, the NHS procurement cycle is complex. Yes, it takes longer than selling to private healthcare. But those who take the time to understand the system, build the right relationships, and prove their value through solid evidence are finding success. The NHS isn't just another market - it's potentially the most valuable partner a healthtech startup could have.



The Exit Strategy: Building for Long-Term Success



The NHS innovation landscape paints a stark contrast to Silicon Valley's exit playbook. While traditional tech startups often sprint toward acquisition, healthtech companies building solutions for the NHS need a fundamentally different approach to long-term success.


Rather than focusing solely on commercial metrics, sustainable success in the NHS ecosystem requires a deeper integration strategy. SWFT Clinical Services exemplifies this approach. By reinvesting profits back into local healthcare and achieving the Social Enterprise Mark, they've created a model that other trusts actively want to protect and grow - a far cry from the traditional "build and sell" mentality.


The most valuable exits often don't look like exits at all. PropCare shows how this evolution works in practice. By aligning their facilities management directly with clinical outcomes and building clear governance structures, they've transformed from a service provider into a core operational capability. According to the Grant Thornton report, this type of deep integration often delivers better long-term value than traditional exit routes.


What's particularly interesting is how this model is reshaping venture capital expectations. While traditional VCs might display caution at investing over considerably longer timelines, those who understand the NHS ecosystem recognize that sustainable integration can actually provide more stable returns than quick flips. Viapath's success illustrates this perfectly - their £100 million annual turnover came not from rushing to exit, but from methodically building trust and capability across multiple NHS organisations.


For healthtech founders, this requires a fundamental mental shift. The focus needs to be on building sustainable value rather than positioning for a quick exit. Success metrics shift from traditional KPIs like user growth to more complex measures like clinical outcome improvements and system-wide efficiency gains.


This isn't to say traditional exits are impossible - Babylon's journey shows there's still room for significant commercial success. But the companies that truly thrive in the NHS ecosystem are those that understand they're building for the long haul. They're not just creating products; they're becoming essential partners in the NHS's ongoing transformation.


The NHS innovation landscape defies conventional exit strategies. While Silicon Valley celebrates quick acquisitions, the most successful healthtech companies in the NHS ecosystem are writing a different story.


Rather than focusing solely on commercial metrics, sustainable success requires deeper integration into the NHS's operational fabric. Viapath demonstrates this perfectly - their £100 million annual turnover wasn't built through rapid scaling, but through methodically building trust and capability across multiple NHS organisations. By choosing an LLP structure and maintaining majority NHS ownership (66.6%), they created a model that balances commercial freedom with public sector values.


The most valuable exits often don't look like exits at all. Consider Guy's and St Thomas' Essentia Trading Limited. Starting from zero revenue in 2013, they've grown to £6.8 million by 2017, with over 20% now coming from international work. They achieved this not by positioning for acquisition, but by becoming an indispensable part of healthcare infrastructure delivery, as noted in the Grant Thornton report.


What's particularly interesting is how this model is reshaping venture capital expectations. Traditional VCs might display caution at longer investment horizons, but those who understand the NHS ecosystem recognize that sustainable integration can actually provide more stable returns. When PropCare launched, they didn't just create another facilities management company - they built governance structures and operational alignments that made them essential to their trust's future.


For healthtech founders, this requires a fundamental shift in mindset. Success metrics move away from traditional KPIs toward measures like clinical outcome improvements and system-wide efficiency gains. While traditional exits remain possible - as Babylon's journey shows - the companies that truly thrive are those building for the long haul, transforming from vendors into partners in the NHS's ongoing evolution.



The venture capital world often speaks of "time to exit," but in NHS innovation, perhaps we need to start talking about "time to integration." While the traditional startup playbook emphasises rapid scaling and quick exits, the NHS market demands a fundamentally different approach - one where success is measured not in quarters, but in years of sustained impact.


For VCs and founders alike, this means rethinking both investment theses and growth strategies. The winners in this space won't be those who move fastest, but those who build most thoughtfully. As the healthtech sector continues to mature, the question isn't whether to engage with the NHS, but how to do so in a way that creates genuine, lasting value. The answer, as we've seen, lies in viewing the NHS not as a market to be conquered, but as a partner in long-term transformation.


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